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Catalog Number Size Price
LS-B11087-50 50 µl (1 mg/ml) $440 
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
AIF1 / IBA1 Antibody - A: 50 µg mouse brain lysate/extract. 15 % SDS-PAGE. AIF1 / IBA1 antibody diluted at 1:1000.
AIF1 / IBA1 Antibody - A: 30 µg THP-1 whole cell lysate/extract. B: 30 µg HL-60 whole cell lysate/extract. 15% SDS PAGE. AIF1 / IBA1 antibody diluted at 1:1000.
AIF1 / IBA1 Antibody - Sample (30 ug of whole cell lysate). A: Molt-4 . 15% SDS PAGE. AIF1 / IBA1 antibody diluted at 1:1000.
AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
AIF1 / IBA1 Antibody - A: 50 µg mouse brain lysate/extract. 15 % SDS-PAGE. AIF1 / IBA1 antibody diluted at 1:1000.
AIF1 / IBA1 Antibody - A: 30 µg THP-1 whole cell lysate/extract. B: 30 µg HL-60 whole cell lysate/extract. 15% SDS PAGE. AIF1 / IBA1 antibody diluted at 1:1000.
AIF1 / IBA1 Antibody - Sample (30 ug of whole cell lysate). A: Molt-4 . 15% SDS PAGE. AIF1 / IBA1 antibody diluted at 1:1000.
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PathPlus™ Polyclonal Rabbit anti‑Human AIF1 / IBA1 Antibody (aa85‑147, IHC, WB) LS‑B11087

PathPlus™ Polyclonal Rabbit anti‑Human AIF1 / IBA1 Antibody (aa85‑147, IHC, WB) LS‑B11087

Note: This antibody replaces LS-C185332
Antibody:
AIF1 / IBA1 Rabbit anti-Human Polyclonal (aa85-147) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-B11087-50
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
AIF1 / IBA1 Rabbit anti-Human Polyclonal (aa85-147) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
AIF1 (allograft inflammatory factor 1, IBA1) is an actin- and calcium-binding protein that enhances membrane ruffling and RAC activation. It is expressed in microglia in the central nervous system and in macrophages, where it plays a role in RAC signaling, phagocytosis, macrophage activation and function, vascular inflammation. Furthermore, it promotes the proliferation of vascular smooth muscle cells and T-lymphocytes. In immunohistochemistry, AIF1 serves as a marker for microglia and for macrophages. In cancer, it can also be used to differentiate malignant reticuloses (AIF1 positive) from astrocytomas (negative). In normal tissues, AIF1 has cytoplasmic and membranous positivity in immune cells, with particularly high expression in macrophages in the lung. References: J Neurochem. 2004 Feb;88(4):844-56, PMID: 14756805; Mol Med. 2015; 21(1): 233–241, PMID: 25569805; Neuroscience and Behavioral Physiology. March 2016, Volume 46, Issue 3, pp 284–290; J Toxicol Pathol. 2013 Mar; 26(1): 55–60, PMID: 23723569
Target
Human AIF1 / IBA1
Synonyms
AIF1 | AIF-1 | Em:AF129756.17 | G1 | IRT-1 | Protein G1 | IBA1 | IRT1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Iba1. The exact sequence is proprietary.
Epitope
aa85-147
Specificity
Human AIF1 / IBA1
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:3000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
1X PBS, pH 7, 0.025% ProClin™ 300, 20% Glycerol, 1% BSA
Storage
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About AIF1 / IBA1
P55008 NM_004847 NP_004838.1

Validation

AIF1 / IBA1 Antibody - Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-AIF1 / IBA1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ AIF1 / IBA1 Antibody (aa85-147) for IHC, WB/Western LS-B11087 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 2/26/2024