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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A6871-50 50 µg (1 mg/ml) $425 
TAOK1 / TAO1 Antibody - Brain, Amygdala, neurons and glia
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Brain, Cortex, neurons and glia
TAOK1 / TAO1 Antibody - Brain, Medulla, neurons of the lateral cuneate nucleus
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Anti-TAOK1 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Brain, Amygdala, neurons and glia
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Brain, Cortex, neurons and glia
TAOK1 / TAO1 Antibody - Brain, Medulla, neurons of the lateral cuneate nucleus
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Anti-TAOK1 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ TAOK1 / TAO1 Antibody Internal Polyclonal IHC LS‑A6871

PathPlus™ TAOK1 / TAO1 Antibody Internal Polyclonal IHC LS‑A6871

Antibody:
Rabbit Polyclonal to Human TAOK1 / TAO1
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A6871-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human TAOK1 / TAO1
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
TAO kinase 1 (TAOK1) acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. TAOK1 is involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, it plays a role in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. TAOK1 acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human TAOK1 / TAO1
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Xenopus (tested or 100% immunogen sequence identity)
Predicted
Chicken, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (4.4 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 16 amino acid peptide from internal region of human TAOK1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig, Platypus, Xenopus (100%); Opossum, Turkey, Chicken, Zebrafish (94%); Stickleback, Pufferfish (88%).
Blocking Peptide
LS-E29199 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A6871. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Internal
Specificity
Human TAOK1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TAOK3 (63%).
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TAOK1 / TAO1
Q7L7X3 NM_020791 NP_065842.1

Validation

TAOK1 / TAO1 Antibody - Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia
Brain, Amygdala, neurons and glia

TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 / TAO1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 / TAO1 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TAOK1 / TAO1 Antibody - Brain, Cortex, neurons and glia
Brain, Cortex, neurons and glia
Brain, Cortex, neurons and glia

TAOK1 / TAO1 Antibody - Brain, Medulla, neurons of the lateral cuneate nucleus
Brain, Medulla, neurons of the lateral cuneate nucleus
Brain, Medulla, neurons of the lateral cuneate nucleus

TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TAOK1 / TAO1 Antibody - Anti-TAOK1 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 antibody IHC of human brain, hippocampus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 / TAO1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-TAOK1 / TAO1 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Requested From: United States
Date Requested: 11/22/2019