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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A552-50 50 µg (1 mg/ml) $425 
RXFP4 / GPR100 Antibody - Pancreas, carcinoma
RXFP4 / GPR100 Antibody - Breast, Carcinoma
RXFP4 / GPR100 Antibody - Hodgkin's lymphoma
RXFP4 / GPR100 Antibody - Anti-RXFP4 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
RXFP4 / GPR100 Antibody - Colon, Carcinoma
RXFP4 / GPR100 Antibody - Pancreas, carcinoma
RXFP4 / GPR100 Antibody - Breast, Carcinoma
RXFP4 / GPR100 Antibody - Hodgkin's lymphoma
RXFP4 / GPR100 Antibody - Anti-RXFP4 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
RXFP4 / GPR100 Antibody - Colon, Carcinoma
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PathPlus™ Polyclonal Rabbit anti‑Human RXFP4 / GPR100 Antibody (C‑Terminus, IHC) LS‑A552

PathPlus™ Polyclonal Rabbit anti‑Human RXFP4 / GPR100 Antibody (C‑Terminus, IHC) LS‑A552

Antibody:
Rabbit Polyclonal to Human RXFP4 / GPR100
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A552-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human RXFP4 / GPR100
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
RXFP4 is a receptor with high affinity for INSL5. It also binds RLN3/relaxin-3, bradykinin and kallidin. Binding of ligands to RXFP4 results in an inhibition of adenylate cyclase. It may play an important role in autocrine and paracrine signaling and the regulation of insulin secretion and ß-cell homeostasis in the normal colon and also in neuroendocrine tumors. In immunohistochemistry, RXFP4 has moderate membranous positivity throughout the central nervous system, and in peripheral tissues is found on neuroendocrine cells, in adrenal tissue, smooth muscle, and on epithelial cells in various tissues including the colon, pancreas, breast, prostate and endometrium. References: Br J Pharmacol. 2007 Mar; 150(6): 677–691, PMID: 17293890; Oncol Rep. 2013 Jan;29(1):149-54, PMID: 23128569
Target
Human RXFP4 / GPR100
Synonyms
RXFP4 | G-protein coupled receptor 100 | GPR100 | JEG62 | G protein-coupled receptor 100 | GPCR142 | Relaxin 3 receptor 2 | RLN3R2 | RXFPR4 | Relaxin-3 receptor 2 | RLN3 receptor 2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 18 amino acid peptide from C-Terminus of human RXFP4. Percent identity with other species by BLAST analysis: Gorilla, Gibbon, Monkey (94%); Human (89%); Bat, Bovine, Rabbit, Horse (83%).
Blocking Peptide
LS-E29075 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A552. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human RXFP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About RXFP4 / GPR100
Q8TDU9 NM_181885 NP_871001.1

Validation

RXFP4 / GPR100 Antibody - Pancreas, carcinoma
Pancreas, carcinoma
Pancreas, carcinoma

RXFP4 / GPR100 Antibody - Breast, Carcinoma
Breast, Carcinoma
Breast, Carcinoma

RXFP4 / GPR100 Antibody - Hodgkin's lymphoma
Hodgkin's lymphoma
Hodgkin's lymphoma

RXFP4 / GPR100 Antibody - Anti-RXFP4 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP4 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-RXFP4 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

RXFP4 / GPR100 Antibody - Colon, Carcinoma
Colon, Carcinoma
Colon, Carcinoma

LSBio Ratings

PathPlus™ RXFP4 / GPR100 Antibody (C-Terminus) for IHC LS-A552 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 5/29/2020