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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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Catalog Number Size Price
LS-A6577-50 50 µg (1 mg/ml) $425 
P2RY14 / GPR105 Antibody - Lung, non small cell carcinoma
P2RY14 / GPR105 Antibody - Anti-P2RY14 / GPR105 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
P2RY14 / GPR105 Antibody - Anti-P2RY14 / P2Y14 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
P2RY14 / GPR105 Antibody - Lung, non small cell carcinoma
P2RY14 / GPR105 Antibody - Anti-P2RY14 / GPR105 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
P2RY14 / GPR105 Antibody - Anti-P2RY14 / P2Y14 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human P2RY14 / GPR105 Antibody (Extracellular Domain, IHC) LS‑A6577

PathPlus™ Polyclonal Rabbit anti‑Human P2RY14 / GPR105 Antibody (Extracellular Domain, IHC) LS‑A6577

Antibody:
Rabbit Polyclonal to Human P2RY14 / GPR105
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A6577-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human P2RY14 / GPR105
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Purinergic receptor P2Y, G-protein coupled, 14 (P2RY14) is a receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. P2RY14 has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it also plays a role in neuroimmune function. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human P2RY14 / GPR105
Synonyms
P2RY14 | G-protein coupled receptor 105 | p2Y purinoceptor 14 | p2Y(14) receptor | p2Y14 receptor | UDP-glucose receptor | p2Y14 | VTR 15-20 receptor | G protein-coupled receptor 105 | GPR105 | KIAA0001 | p2RY14
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (11 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 17 amino acid peptide from 2nd extracellular domain of human P2RY14 / P2Y14. Percent identity with other species by BLAST analysis: Human (100%); Monkey (94%); Marmoset (88%).
Blocking Peptide
LS-E29141 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A6577. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Extracellular Domain
Specificity
Human P2RY14 / P2Y14. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About P2RY14 / GPR105
Q15391 NM_014879 NP_055694.3

Validation

P2RY14 / GPR105 Antibody - Lung, non small cell carcinoma
Lung, non small cell carcinoma
Lung, non small cell carcinoma

P2RY14 / GPR105 Antibody - Anti-P2RY14 / GPR105 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY14 / GPR105 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY14 / GPR105 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

P2RY14 / GPR105 Antibody - Anti-P2RY14 / P2Y14 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY14 / P2Y14 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-P2RY14 / P2Y14 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ P2RY14 / GPR105 Antibody (Extracellular Domain) for IHC LS-A6577 has an LSBio Rating of
Laboratory Validation Score (5)

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Requested From: United States
Date Requested: 5/28/2020