Menu
Products
Services
Research Areas
Resources
Contact Us
Distributors
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Services
Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121
Phone:
866-819-4732 (Toll Free North America
206-374-1102 (International)
Fax:
866-206-6909 (Toll Free North America)
206-577-4565 (International)
How To Buy - Details about how to buy our products.
Orders@LSBio.com - To submit a new order.
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, froforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information about an LSBio product or its applications
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.
Worldwide Distributors List - To find your local distributor if you're not within the United States.
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Catalog Number Size Price
LS-B8475-50 50 µg (1 mg/ml) $485 
KCNJ2 / Kir2.1 Antibody - Anti-KCNJ2 / KIR2.1 antibody IHC of human lung, alveoli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.

PathPlus™ Polyclonal KCNJ2 / Kir2.1 Antibody (IHC, WB) LS‑B8475

PathPlus™ Polyclonal KCNJ2 / Kir2.1 Antibody (IHC, WB) LS‑B8475

Note: This antibody replaces LS-C154769
Antibody:
Chicken Polyclonal to Human KCNJ2 / Kir2.1
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$485 
LS-B8475-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Chicken Polyclonal to Human KCNJ2 / Kir2.1
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
KCNJ2 (Kir2.1 inward-rectifier potassium ion channel) is a potassium ion channel protein that maintains resting membrane potential and regulates cell excitability. It plays an important role in neural and craniofacial development. It is highly expressed in the hippocampus, nucleus accumbens, putamen and caudate in the brain as well as in skeletal muscle, and is central to the inward-rectifier current (IK1) that controls cardiac excitability in human ventricular muscle. Mutations in KCNJ2 affect neuronal excitability and are associated with Autism, short-QT syndrome and Andersen-Tawil syndrome. In immunohistochemistry, KCNJ2 has cytoplasmic positivity in most tissues throughout the body. References: Front. Cell. Neurosci. 2018, DOI: 10.3389/fncel.2018.00076; Heart Rhythm. 2005 Mar;2(3):316-24, PMID: 15851327; Cardiovascular Research. 2012. 93 (4): 666–673, DOI:10.1093/cvr/cvr329; J Physiol. 2016 Jun 15;594(12):3245-70, PMID: 26864374
Target
Human KCNJ2 / Kir2.1
Synonyms
KCNJ2 | ATFB9 | HHBIRK1 | IRK1 | KIR2.1 | LQT7 | HIRK1 | IRK-1 | HHIRK1 | SQT3
Host
Chicken
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgY Polyclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot (1:200 - 1:2000)
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide derived from Cter domain of human Kir2.1
Specificity
Reacts with a 48 kDa protein. Cross reacts with other species due to sequence homology.
Presentation
K2HPO4/KH2PO4, Glycerol 50%, (pH 7.5)
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KCNJ2 / Kir2.1
P63252 NM_000891 NP_000882.1

Validation

KCNJ2 / Kir2.1 Antibody - Anti-KCNJ2 / KIR2.1 antibody IHC of human lung, alveoli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Anti-KCNJ2 / KIR2.1 antibody IHC of human lung, alveoli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Anti-KCNJ2 / KIR2.1 antibody IHC of human lung, alveoli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.

Publications (0)

Customer Reviews (0)


Requested From: United States
Date Requested: 2/25/2020