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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A921-50 50 µg (1 mg/ml) $425 
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM7 / MGLUR7 Antibody - Eye, Retina
GRM7 / MGLUR7 Antibody - Brain, Hypothalamus
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM7 / MGLUR7 Antibody - Eye, Retina
GRM7 / MGLUR7 Antibody - Brain, Hypothalamus
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ GRM7 / MGLUR7 Antibody N‑Terminus Polyclonal ICC,IHC,WB LS‑A921

PathPlus™ GRM7 / MGLUR7 Antibody N‑Terminus Polyclonal ICC,IHC,WB LS‑A921

Antibody:
Rabbit Polyclonal to Human GRM7 / MGLUR7
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human, Bovine
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A921-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human GRM7 / MGLUR7
Application:
IHC, IHC-P, ICC, WB
Reactivity:
Human, Bovine
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Glutamate receptor, metabotropic 7 (GRM7) is a receptor for glutamate, the primary excitatory neurotransmitter in the central nervous system. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GRM7 / MGLUR7
Host
Rabbit
Reactivity
Human, Bovine (tested or 100% immunogen sequence identity)
Predicted
Monkey, Mouse, Rat, Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (6 - 16 µg/ml)
  • ICC
  • Western blot
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human GRM7 / MGLUR7. Percent identity with other species by BLAST analysis: Human, Elephant, Bovine (100%); Chimpanzee, Gorilla, Orangutan, Monkey, Marmoset, Mouse, Rat, Dog, Horse (95%); Gibbon, Panda, Rabbit, Opossum (89%); Chicken, Xenopus (84%).
Blocking Peptide
LS-E29572 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A921. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human GRM7 / MGLUR7. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRM8 (63%).
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GRM7 / MGLUR7
Q14831 NM_000844 NP_000835.1

Validation

GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM7 / MGLUR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM7 / MGLUR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM7 / MGLUR7 Antibody - Eye, Retina
Eye, Retina
Eye, Retina

GRM7 / MGLUR7 Antibody - Brain, Hypothalamus
Brain, Hypothalamus
Brain, Hypothalamus

GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM7 / MGLUR7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM7 / MGLUR7 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM7 / MGLUR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM7 / MGLUR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GRM7 / MGLUR7 Antibody - Anti-GRM7 / MGLUR7 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM7 / MGLUR7 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GRM7 / MGLUR7 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Requested From: United States
Date Requested: 11/15/2019