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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A4257-50 50 µg (1 mg/ml) $425 
GCGR / Glucagon Receptor Antibody - Brain, Glioblastoma
GCGR / Glucagon Receptor Antibody - Adipose tissue, Liposarcoma
GCGR / Glucagon Receptor Antibody - Anti-GCGR / Glucagon Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GCGR / Glucagon Receptor Antibody - Anti-GCGR / Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GCGR / Glucagon Receptor Antibody - Anti-Glucagon Receptor antibody IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GCGR / Glucagon Receptor Antibody - Brain, Glioblastoma
GCGR / Glucagon Receptor Antibody - Adipose tissue, Liposarcoma
GCGR / Glucagon Receptor Antibody - Anti-GCGR / Glucagon Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GCGR / Glucagon Receptor Antibody - Anti-GCGR / Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GCGR / Glucagon Receptor Antibody - Anti-Glucagon Receptor antibody IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ Polyclonal Rabbit anti‑Human GCGR / Glucagon Receptor Antibody (N‑Terminus, IHC) LS‑A4257

PathPlus™ Polyclonal Rabbit anti‑Human GCGR / Glucagon Receptor Antibody (N‑Terminus, IHC) LS‑A4257

Antibody:
Rabbit Polyclonal to Human GCGR / Glucagon Receptor
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Dog, Hamster, Horse
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A4257-50
50 µg
1 mg/ml

Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human GCGR / Glucagon Receptor
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Bovine, Dog, Hamster, Horse
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
Glucagon receptor (GCGR) mediates the effects of glucagon in controlling glucose metabolism by initiating a cascade of events that regulate the amount of glucose released from the liver into the bloodstream. Glucagon generally functions as a counterregulatory hormone, opposing the actions of insulin, in maintaining the levels of blood glucose, particularly in patients with hypoglycemia. In patients with diabetes, excess glucagon secretion plays a primary role in the metabolic perturbations associated with diabetes, such as hyperglycemia. References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human GCGR / Glucagon Receptor
Synonyms
GCGR | GL-R | Glucagon receptor | GGR
Host
Rabbit
Reactivity
Human, Monkey, Bovine, Dog, Hamster, Horse (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (15 - 20 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 18 amino acid peptide from N-Terminus extracellular domain of human Glucagon Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Hamster, Bovine, Dog, Horse (100%); Mouse, Rat (94%).
Blocking Peptide
LS-E28926 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A4257. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human Glucagon Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GCGR / Glucagon Receptor
P47871 NM_000160 NP_000151.1

Validation

GCGR / Glucagon Receptor Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

GCGR / Glucagon Receptor Antibody - Adipose tissue, Liposarcoma
Adipose tissue, Liposarcoma
Adipose tissue, Liposarcoma

GCGR / Glucagon Receptor Antibody - Anti-GCGR / Glucagon Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GCGR / Glucagon Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GCGR / Glucagon Receptor antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GCGR / Glucagon Receptor Antibody - Anti-GCGR / Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GCGR / Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GCGR / Glucagon Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GCGR / Glucagon Receptor Antibody - Anti-Glucagon Receptor antibody IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Glucagon Receptor antibody IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-Glucagon Receptor antibody IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

LSBio Ratings

PathPlus™ GCGR / Glucagon Receptor Antibody (N-Terminus) for IHC LS-A4257 has an LSBio Rating of
Laboratory Validation Score (5)

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Requested From: United States
Date Requested: 5/30/2020