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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-A3990-50 50 µg (1 mg/ml) $425 
ADRA2C Antibody - Brain, Pituitary
ADRA2C Antibody - Brain, hippocampus
ADRA2C Antibody - Anti-ADRA2C antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ADRA2C Antibody - Anti-ADRA2C antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ADRA2C Antibody - Anti-ADRA2C antibody IHC of human brain, neurons of area ca1. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ADRA2C Antibody - Brain, Pituitary
ADRA2C Antibody - Brain, hippocampus
ADRA2C Antibody - Anti-ADRA2C antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ADRA2C Antibody - Anti-ADRA2C antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
ADRA2C Antibody - Anti-ADRA2C antibody IHC of human brain, neurons of area ca1. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PathPlus™ ADRA2C Antibody Extracellular Domain Polyclonal IHC LS‑A3990

PathPlus™ ADRA2C Antibody Extracellular Domain Polyclonal IHC LS‑A3990

Note: This antibody replaces LS-C63775
Antibody:
Rabbit Polyclonal to Human ADRA2C
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$425 
LS-A3990-50
50 µg
1 mg/ml
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Human ADRA2C
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
ADRA2C is a member of one of three families of Alpha-2-adrenergic GPCRs that include subtypes alpha2A, alpha2B and alpha2C. These receptors are critical in regulating neurotransmitter release from adrenergic neurons and sympathetic nerves. The alpha2 subtypes are found in the central nervous systm and stimulation is associated with sedation, analgesia, and sympatholytic effects. The alpha2A subtype inhibits transmitter release at high stimulation frequencies, whereas the alpha2C subype modulates neurotransmission at lower levels of nerve activity. Anesth Prog. 2015 Spring; 62(1): 31–38.
Target
Human ADRA2C
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Dog, Guinea pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (15 - 30 µg/ml)
  • Applications tested for the base form of this product only
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic 18 amino acid peptide from 2nd extracellular domain of human ADRA2C. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Mouse, Rat, Panda, Bovine, Dog, Guinea pig (94%); Hamster (89%).
Blocking Peptide
LS-E28859 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A3990. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Extracellular Domain
Specificity
Human ADRA2C. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ADRA2C
P18825 NM_000683 NP_000674.2

Validation

ADRA2C Antibody - Brain, Pituitary
Brain, Pituitary
Brain, Pituitary

ADRA2C Antibody - Brain, hippocampus
Brain, hippocampus
Brain, hippocampus

ADRA2C Antibody - Anti-ADRA2C antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADRA2C antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADRA2C antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ADRA2C Antibody - Anti-ADRA2C antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADRA2C antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADRA2C antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

ADRA2C Antibody - Anti-ADRA2C antibody IHC of human brain, neurons of area ca1. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADRA2C antibody IHC of human brain, neurons of area ca1. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-ADRA2C antibody IHC of human brain, neurons of area ca1. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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Requested From: United States
Date Requested: 11/20/2019