Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
LS-F1771 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Qualitative detection of Human TP53BP1 / 53BP1 in samples of Adherent Cell Cultures. It is based upon a Cell-Based assay principle.
TP53BP1, 53BP1, p202, p53-binding protein 1, p53-binding protein 53bp1, p53BP1
Mouse, Human, Rat
Intended Sample Types
Adherent Cell Cultures
Colorimetric - 450nm (TMB)
Short term: 4°C; Long term: see manual.
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
Tumor protein p53 binding protein 1 binds to the central domain of p53 required for site-specific DNA binding thus inhibiting the ability of p53 to bind DNA. TP53BP1 also functions as a checkpoint protein with properties of a DNA double-strand break sensor. It is a putative substrate of ATM kinase and is phosphorylated in response to DNA damage and localizes to sites of double-strand breaks.