Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
LS-F37871 is a 96-well enzyme-linked immunosorbent assay (ELISA) for the Quantitative detection of Human GJB3 / CX31 / Connexin 31 in samples of Plasma and Serum. It is based upon a Sandwich assay principle and can be used to detect levels of GJB3 / CX31 / Connexin 31 as low as 0.188 nanograms per millilter.
GJB3, Connexin 31, Connexin-31, CX31, DFNA2, Erythrokeratodermia variabilis, Gap junction beta-3 protein, DFNA2B, EKV, Gap junction protein beta 3
Intended Sample Types
12 x 8-Well Microstrips
Colorimetric - 450nm (TMB)
0.313 - 20 ng/ml
Intra-Assay: CV<15% Inter-Assay: CV<15%
Short term: 4°C; Long term: see manual.
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
GJB3 / CX31 / Connexin 31 is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.