Sandwich ELISA (enzyme-linked immunosorbent assay) kit
This kit is for the detection of natural and recombinant human ANGPTL3. No significant cross-reactivity or interference between ANGPTL3 and analogs was observed.
Intended Sample Types
Cell Culture Supernatants, Plasma, Serum
Colorimetric - 450nm (TMB)
312 - 20000 pg/ml
Intra-Assay: CV%<4.7% Inter-Assay: CV%<7.4%
Short term: 4°C; Long term: see manual.
Due to their limited shelf life, LSBio ELISA kits are not typically stocked as finished goods. Upon receipt of an order each kit is assembled and tested to ensure that it meets specifications before shipping. Minor changes may occur to the Range, Sensitivity, and Precision. In the event of a significant change the order would be confirmed with the customer before shipping ELISA kit lot numbers reflect the date of final assembly and testing for each specific kit rather than a bulk manufactured lot. All kits are tested to confirm that they fall within their defined Inter- and Intra- assay coefficient of variation.
- Coated 96-well Strip Plate
- Standard (Lyophilized)
- Biotinylated Detection Antibody (100x)
- ABC Complex (100x)
- Sample Diluent
- Detection Antibody Diluent
- ABC Complex Diluent
- TMB Substrate
- Stop Solution
- Adhesive Plate Sealers
ANGPTL3, also known as Angiopoietin-like 3 or HYPLl, is a protein that in humans is encoded by the ANGPTL3 gene. It is mapped to 1p31.3. The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is expressed predominantly in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain, and the C-terminal fibrinogen (FBN)-like domain. ANGPTL3 also acts as dual inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), and increases plasma triglyceride and HDL cholesterol in rodents. It can inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels.
For research use only.