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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.
Gene Name: | wingless-type MMTV integration site family, member 11 |
Family/Subfamily: | WNT , not assigned-WNT |
Synonyms: | WNT11, HWNT11, Protein Wnt-11 |
Target Sequences: | NM_004626 NP_004617.2 O96014 |
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