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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-C14908-100 100 µg $575 
Antibody

Polyclonal Rabbit anti‑Human TNFRSF10A / DR4 Antibody (N‑Terminus, WB) LS‑C14908

Polyclonal Rabbit anti‑Human TNFRSF10A / DR4 Antibody (N‑Terminus, WB) LS‑C14908

Antibody:
Rabbit Polyclonal to Human TNFRSF10A / DR4
Application:
WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Price
Catalog Number
$575 
LS-C14908-100
100 µg
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
Rabbit Polyclonal to Human TNFRSF10A / DR4
Application:
WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:

Specifications

Description
DR4 antibody LS-C14908 is an unconjugated rabbit polyclonal antibody to human DR4 (TNFRSF10A) (N-Terminus). Validated for WB.
Target
Human TNFRSF10A / DR4
Synonyms
TNFRSF10A | APO2 | CD261 | DR4 | TRAIL-R1 | TRAILR-1 | TRAILR1 | TRAIL receptor 1 | CD261 antigen | Cytotoxic TRAIL receptor | Death receptor 4
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, Biotin, FITC, HRP, PE.
Purification
Ion exchange chromatography
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
Immunogen
Peptide from N-Terminus of human DR4.
Epitope
N-Terminus
Specificity
Recognizes the 57kD apoptosis related protein designated DR-4 (death receptor 4). DR4 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95. The ligand for DR-4 is TRAIL and thus DR-4 has also been called TRAIL-RI. DR4 is expressed in most human tissues. In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals.
Usage
Western Blot: 1:500-1:1000.
Presentation
PBS, 0.02% Sodium Azide
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About TNFRSF10A / DR4
NM_003844

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Requested From: United States
Date Requested: 7/5/2020