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Thyrotropin / TSH Antibody LS‑C42181

Catalog Number Size Price
LS-C42181-50 50 µl $485 
Antibody

Thyrotropin / TSH Antibody LS‑C42181

Antibody:
Rabbit Polyclonal to Dog Thyrotropin / TSH
Application:
IHC-Fr, ELISA
Reactivity:
Dog
Format:
Unconjugated, Unmodified
Price
Catalog Number
$485 
LS-C42181-50
Toll Free North America
866-819-4732

Overview

Antibody:
Rabbit Polyclonal to Dog Thyrotropin / TSH
Application:
IHC-Fr, ELISA
Reactivity:
Dog
Format:
Unconjugated, Unmodified

Specifications

Description
TSH antibody LS-C42181 is an unconjugated rabbit polyclonal antibody to dog TSH (Thyrotropin ). Validated for ELISA and IHC.
Target
Dog Thyrotropin / TSH
Host
Rabbit
Reactivity
Dog (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • IHC - Frozen
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Purified canine TSH.
Specificity
Polyclonal antibody was raised against highly purified intact canine thyroid stimulating hormone (TSH) and is specific for canine TSH. Exhibits less than 0.1% cross reactivity with the other major canine glycoprotein hormones; growth hormone (GH), luteinizing hormone (LH) and follicle stimulating hormone (FSH) or prolactin using an iodinated hormone tracer assay. This strongly indicates thatantibody is primarily reactive with the TSHbeta chain although it may also have reactivity with beta chain conformational epitopes dependent on the presence of the common alpha chain shared with the other glycoprotein hormones. TSH, also known as thyrotropin is synthesized in, and secreted from within the anterior pituitary gland, under the influence of secreted thyrotropin releasing hormone from the hypothalamus. TSH is composed of, as are the other major glycoprotein hormones, a common alpha chain non-covalently linked to a unique beta chain responsible for conferring the structural and biological identity of the individual hormone. TSH binds to the TSH receptor (TSHR) in the thyroid gland. TSHR has also bee detected in other cell types including adipocytes, neuronal cells and gastric mucosa. Defects in the TSHbeta subunit can lead to hypothyroidism, either through the lack of secreted hormone or secretion of TSH lacking full biological acticvity.
Presentation
PBS
Reconstitution
50 µl ddH2O
Storage
Before reconstitution store at 4°C. After reconstitution store at -20°C. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee

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Requested From: United States
Date Requested: 9/15/2019