Human TF / Transferrin
TF | PRO1557 | Serotransferrin | Siderophilin | TFQTL1 | Beta-1 metal-binding globulin | Transferrin | PRO2086
(tested or 100% immunogen sequence identity)
Native human TF / Transferrin.
Recognizes human transferrin, an approximately 80kD blood plasma glycoprotein synthesized by the liver, which contains two specific high affinity iron (Fe3+) binding sites and is responsible for the transport and supply of an exchangeable pool of iron, through binding to cell surface transferrin receptors. Transferrin is the primary blood iron transport protein and under normal conditions, approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anemia, iron overload and hemochromatosis. Shows minimal cross reactivity with related serum proteins.