Human STRA8

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide from the C-Terminus of human Stra8 (DEEMIMLQCTETFDDEDL, aa313-330 of UniProt Q7Z7C7). Percent identity by BLAST analysis: Human (100%); Sheep, Bovine (89%); Cat, Horse, Pig, Guinea pig, Dog (83%).

aa313-330

Human STRA8

• Western blot (0.5 - 1 µg/ml)

Stimulated by retinoic acid 8 is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons and is mapped to chromosome 7q31. Retinoic acid (RA) signaling is required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying expression in embryonic testis. Since RA signaling regulated expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q7Z7C7 NCBI: Q7Z7C7