Target
Human STAT1
Synonyms
STAT1 | ISGF-3 | STAT91 | CANDF7
Reactivity
Human, Dog, Horse
(tested or 100% immunogen sequence identity)
Immunogen
A 39 residue synthetic peptide VHPSRLQTTDNLLPMSPEEFDEVSRIVGSVEFDSMMNTV based on the human STAT1alpha (aa 712-750) was synthesized and the peptide coupled to KLH. The sequence differs from that of mouse by four amino acids. The C-Terminus 38. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Panda, Dog, Horse (100%); Marmoset, Sheep, Elephant, Bovine, Bat (97%); Pig (94%); Mouse, Hamster, Rabbit (87%); Opossum (84%); Rat (81%).
Specificity
Detects a ~97kD protein, corresponding to the apparent molecular mass of STAT1alpha on SDS-PAGE immunoblots, in human, mouse, rat and bovine cell lysates and tissue extracts. This antibody does not detect the 84kD STAT1beta.