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Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
Gene Name: | slingshot protein phosphatase 2 |
Family/Subfamily: | Protein Phosphatase , Slingshot |
Synonyms: | SSH2, HSSH-2L, KIAA1725, Slingshot 2, SSH-2L, SSH-like protein 2, SSH2L, SSH-2 |
Target Sequences: | AB072358 BAB84117.1 Q76I76 |
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