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| Catalog Number | Size | Price |
|---|---|---|
| LS-C389261-100 | 100 µg | $575 |
1 of 2
2 of 2
Polyclonal Rabbit anti‑Human SOCS1 Antibody (aa197‑211, IHC, WB) LS‑C389261
Polyclonal Rabbit anti‑Human SOCS1 Antibody (aa197‑211, IHC, WB) LS‑C389261
Antibody:
SOCS1 Rabbit anti-Human Polyclonal (aa197-211) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
SOCS1 Rabbit anti-Human Polyclonal (aa197-211) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit
Format:
Unconjugated, Unmodified
Specifications
Description
SOCS1 antibody LS-C389261 is an unconjugated rabbit polyclonal antibody to SOCS1 (aa197-211) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB.
Target
Human SOCS1
Synonyms
SOCS1 | CIS1 | CISH1 | JAB | JAK-binding protein | JAK binding protein | STAT-induced STAT inhibitor 1 | SSI-1 | Tec-interacting protein 3 | TIP3 | SOCS-1 | SSI1 | STAT induced SH3 protein 1 | TIP-3
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from the C-Terminus of human SOCS1 (NPVLRDYLSSFPFQI, aa197-211 of UniProt O15524). Percent identity by BLAST analysis: Human, Mouse, Rat, Ferret, Bovine, Bat, Hamster, Elephant, Rabbit, Horse, Pig, Guinea pig, Dog (100%); Opossum, Turkey, Zebra finch, Chicken (87%); Xenopus (80%).
Epitope
aa197-211
Specificity
Human SOCS1
Applications
- IHC
- IHC - Paraffin (0.5 - 1 µg/ml)
- Western blot (0.5 - 1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Suppressor of cytokine signaling 1 (SOCS1), also known as Jak-binding protein (JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About SOCS1
Publications (0)
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Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Species:
Mouse
Applications:
Western blot, Immunoprecipitation, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/27/2024
Date Requested: 4/27/2024
