Sm / Smith antibody was raised against sm (Smith) Antigen. Cellular Localization: Nuclear. MW of Antigen: ~25kD (predominant)
Recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. Precipitates the small nuclear RNAs U1, U2, U4, U5 and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes. Species cross-reactivity: Human, porcine, rabbit, rat and Drosophila.
PBS, pH 7.2, No preservatives added
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