Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms.
Gene Name: | solute carrier family 12 (potassium/chloride transporter), member 5 |
Family/Subfamily: | Transporter , Cation:chloride symporter |
Synonyms: | SLC12A5, Erythroid K-Cl cotransporter 2, HKCC2, K-Cl cotransporter 2, KCC2, KIAA1176, Neuronal K-Cl cotransporter |
Target Sequences: | NM_020708 NP_065759.1 Q9H2X9 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.