Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
SERPINA6 / CBG antibody was raised against synthetic peptide C-KASQQINQHVKDKT from an internal region of rat SERPINA6 / CBG (NP_001009663.1). Percent identity with other species by BLAST analysis: Rat (100%).
LS-E27622 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C139752. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Rat SERPINA6 / CBG.
Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 55kD band observed in Rat Liver lysates (calculated MW of 44.7kD according to NP_001009663.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Richard et al, Endocrinology. 2010 Feb;151(2):649-59; PMID: 20022933). Recommended concentration: 0.03-0.1 ug/ml.
SERPINA6 / CBG is an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.