Mouse SELL / L-Selectin / CD62L

Rabbit

Mouse, Rat (tested or 100% immunogen sequence identity)

Rabbit (at least 90% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Immunoaffinity purified

Unmodified

Synthetic peptide from the middle region of mouse L-Selectin (KEDCVEIYIKRERDSGK, aa125-141 of UniProt P18337). Percent identity by BLAST analysis: Mouse, Rat (100%); Rabbit (94%); Sheep, Bovine, Horse, Pig, Opossum, Dog (88%); Human, Ferret, Cat, Bat, Elephant (82%).

aa125-141

Mouse SELL / L-Selectin / CD62L

• Western blot (0.5 - 1 µg/ml)

L-Selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin)is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a homing receptor for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.

Reconstitute in sterile distilled water.

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

NCBI: NM_000655