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S100A9 / MRP14 Antibody (clone S100A9/1075, Azide-free) LS-C390950

Antibody

S100A9 / MRP14 Antibody (clone S100A9/1075, Azide-free) LS-C390950

Antibody:
Mouse Monoclonal to Human S100A9 / MRP14
Application:
IHC, IHC-P, IF, Flo
Reactivity:
Human, Rat
Format:
Unconjugated, Azide-free
Other formats:
Price
Catalog Number
$465 
LS-C390950-100
Toll Free North America
866-819-4732

Overview

Antibody:
Mouse Monoclonal to Human S100A9 / MRP14
Application:
IHC, IHC-P, IF, Flo
Reactivity:
Human, Rat
Format:
Unconjugated, Azide-free
Other formats:

Specifications

Description
MRP14 antibody LS-C390950 is an unconjugated mouse monoclonal antibody to MRP14 (S100A9) from human and rat. Validated for Flow, IF and IHC.

Target
Human S100A9 / MRP14
Host
Mouse
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Clone
S100A9/1075
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free. Also available Unmodified.
Applications
  • IHC
  • IHC - Paraffin (0.5 - 1 µg/ml)
  • Immunofluorescence (0.5 - 1 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
S100A9 / MRP14 antibody was raised against recombinant human protein.
Specificity
Human S100A9 / MRP14
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This mAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.
Presentation
Sterile Solution PBS
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About S100A9 / MRP14
P06702 NM_002965 NP_002956.1

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Requested From: United States
Date Requested: 5/26/2019
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