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Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general. As a result, may regulate cell adhesion and migration (By similarity). During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis.
Gene Name: | RAB21, member RAS oncogene family |
Family/Subfamily: | Ras GTPase superfamily IPR001806 , RAS oncogene |
Synonyms: | RAB21, KIAA0118, Ras-related protein Rab-21 |
Target Sequences: | NM_014999 NP_055814.1 Q9UL25 |
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