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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PTHR2 / PTH2R Antibody (Extracellular Domain) IHC‑plus™ LS‑A249
PTH2R antibody LS-A249 is an unconjugated rabbit polyclonal antibody to human PTH2R (PTHR2). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-A249-50
50 µg (1 mg/ml)
$425
In Stock for Immediate Shipment

Popular PTHR2 / PTH2R Products

Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Monkey, Bovine
Applications: IHC, IHC - Paraffin, ELISA
Antibody
Species:
Applications: Western blot
Anti-PTH2R / PTHR2 antibody LS-A250 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin
Antibody
Species: Dog
Applications: IHC, ICC, Western blot, Immunoprecipitation

Product Description

PTH2R antibody LS-A249 is an unconjugated rabbit polyclonal antibody to human PTH2R (PTHR2). Validated for IHC. Tested on 20 paraffin-embedded human tissues.

Specifications

Target
Human PTHR2 / PTH2R
Synonyms
PTH2R, Parathyroid hormone 2 receptor, Parathyroid hormone receptor 2, PTH2 receptor, PTHR2, Hpth2 receptor
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (9 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
PTHR2 / PTH2R antibody was raised against synthetic 20 amino acid peptide from 1st extracellular domain of human PTH2R / PTHR2. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (95%).
Blocking Peptide
LS-E28562 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A249. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Extracellular Domain
Specificity
Human PTH2R / PTHR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About PTHR2 / PTH2R
This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. P49190 NM_005048 NP_005039.1


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Images

Immunohistochemistry

Anti-PTH2R / PTHR2 antibody LS-A249 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTH2R / PTHR2 antibody LS-A249 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PTHR2 / PTH2R antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTHR2 / PTH2R antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PTH2R / PTHR2 antibody LS-A249 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTH2R / PTHR2 antibody LS-A249 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PTHR2 / PTH2R antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTHR2 / PTH2R antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PTH2R / PTHR2 antibody LS-A249 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTH2R / PTHR2 antibody LS-A249 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PTHR2 / PTH2R antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTHR2 / PTH2R antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PTH2R / PTHR2 antibody LS-A249 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTH2R / PTHR2 antibody LS-A249 IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-PTHR2 / PTH2R antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTHR2 / PTH2R antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 10/16/2018

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