Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
PTGER1 / EP1 antibody was raised against synthetic 16 amino acid peptide from 1st cytoplasmic domain of human PTGER1 / EP1. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Hamster, Bovine, Dog (94%); Mouse, Rat, Bat (81%).
LS-E29714 - Liquid - 50 µg 1 mg/ml - $145.00
Immunizing peptide used to generate LS-A962. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human PTGER1 / EP1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
PBS, 0.1% Sodium Azide
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Prostaglandin E receptor EP1 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP2, EP3, and EP4), it mediates the diverse biological effects of prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, cervical and colon cancer, induction of labor, control of blood pressure, bone resorption, and asthma.
Antagonism of the prostaglandin E2 EP1 receptor in MDCK cells increases growth through activation of Akt and the epidermal growth factor receptor. Taub M, Parker R, Mathivanan P, Ariff MA, Rudra T. American journal of physiology. Renal physiology. 2015 Sep;307:F539-50. [Full Text Article]