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The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009]
Gene Name: | pregnancy specific beta-1-glycoprotein 1 |
Family/Subfamily: | CEA , not assigned-CEA |
Synonyms: | PSG1, B1G1, CD66f, CD66f antigen, FL-NCA-1/2, PS-beta-G-1, PSBG1, PSG95, PSGGA, PSGIIA, PSBG-1, DHFRP2, PS-beta-C/D |
Target Sequences: | NM_006905 NP_008836.2 P11464 |
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