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Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.
Gene Name: | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
Family/Subfamily: | Non-Protein Kinase , not assigned-Non-Protein Kinase |
Synonyms: | PIK3R3, PI3-kinase subunit p55-gamma, PI3-kinase p85-gamma subunit, p55PIK, p55, p55-GAMMA, p85 Gamma, PI3K regulatory subunit gamma |
Target Sequences: | NM_003629 NP_003620.3 Q92569 |
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