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PANX2 / Pannexin 2 belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | pannexin 2 |
Synonyms: | PANX2, HPANX2, Pannexin 2, Pannexin-2, PX2 |
Target Sequences: | NP_443071.2 Q96RD6 |
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