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NFYC is one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | nuclear transcription factor Y, gamma |
Synonyms: | NFYC, CBF-C, CCAAT binding factor subunit C, CBFC, H1TF2A, HAP5, HSM, Transactivator HSM-1, Transactivator HSM-1/2, NF-YC |
Target Sequences: | NM_014223 NP_055038.2 Q13952 |
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