Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
Gene Name: | nucleic acid binding protein 2 |
Synonyms: | NABP2, LP3587, HSSB1, OBFC2B, Sensor of ssDNA subunit B1, SSB1, SOSS-B1, Nucleic acid binding protein 2, Nucleic acid-binding protein 2, SOSS complex subunit B1 |
Target Sequences: | NM_024068 NP_076973.1 Q9BQ15 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.