Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Western blot, ELISA (applications tested for the base form of this product only)
Unconjugated
Details
Rat IgE
Mouse
Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [MARE-1]
Unconjugated.
Also available conjugated with Biotin, FITC, HRP.
Affinity purified
Unmodified
Applications
Western blot
ELISA (5 µg/ml)
(applications tested for the base form of this product only)
Specificity and Use
Rat IgE antibody was raised against iR162, IR1016, IR2 and IR410 rat IgE myeloma proteins.
Specific for the epsilon chain of rat IgE and does not cross-react with other classes of rat immunoglobulin. May be used as a coating antibody in ELISA.
ELISA: This antibody may be used as a coating antibody in a sandwich ELISA in combination with clone MARK-1/MARL-15 (LS-C57288) as detection reagent and purified rat IgE.
Packaging
PBS, pH 7.4, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.
About Rat IgE
Immunoglobulin E (IgE) is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. Monomers of IgE consist of two heavy chains (epsilon chain) and two light chains, with the epsilon chain containing 4 Ig-like constant domains. IgE's main function is immunity to parasites such as helminths like Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum.