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MMRN2 / Emilin 3 / EndoGlyx-1 is a protein belonging to the member of elastin microfibril interface-located (EMILIN) protein family. This family member is an extracellular matrix glycoprotein that can interfere with tumor angiogenesis and growth. It serves as a transforming growth factor beta antagonist and can interfere with the VEGF-A/VEGFR2 pathway. A related pseudogene has been identified on chromosome 6.
Gene Name: | multimerin 2 |
Synonyms: | MMRN2, ENDOGLYX-1, EndoGlyx-1 p125/p140 subunit, EMILIN-like protein EndoGlyx-1, Multimerin 2, Multimerin-2, EMILIN-3 |
Target Sequences: | NM_024756 NP_079032.2 Q9H8L6 |
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