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Catalog Number Size Price
LS-C744228-1 1 ml $599 
Antibody

Polyclonal Mouse anti‑Human MLANA / Melan‑A Antibody (IHC) LS‑C744228

Polyclonal Mouse anti‑Human MLANA / Melan‑A Antibody (IHC) LS‑C744228

Antibody:
MLANA / Melan-A Mouse anti-Human Polyclonal Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Price
Catalog Number
$599
LS-C744228-1
Toll Free North America
866-819-4732
For Research Use Only

Overview

Antibody:
MLANA / Melan-A Mouse anti-Human Polyclonal Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified

Specifications

Description
Melan-A antibody LS-C744228 is an unconjugated mouse polyclonal antibody to human Melan-A (MLANA). Validated for IHC.
Target
Human MLANA / Melan-A
Synonyms
MLANA | Antigen LB39-AA | Antigen SK29-AA | Melan-A | Protein Melan-A | MART-1 | MART1 | Melan A
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Polyclonal
Conjugations
Unconjugated
Modifications
Unmodified
Immunogen
Recombinant Melan-A protein
Applications
  • IHC - Paraffin (1:10 - 1:20)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Usage
Heat pre-treatment of formalin fixed material with antigen retrieval is recommended. The antibody A103 is suitable for the detection of Melan-A antigen (syn. MART-1) in cells of melanoic origin. The antibody will label 80-90% of metastasing malign melanoma (1, 6). Melan-A-negative melanoma usually are of the spindle cell or desmoblastic type. The antibody also reacts positive with angiomyolipoma (4) and steroid hormone producing cells of the adrenal gland, ovary, testis and especially with carcinoma of these organs. Melan-A is a melanoma specific antigen, which is detected by cytotoxic T-cells. It is exprimed by benign naevi and melanoma cells. 20-22 kDA Melan-A protein, no cross-reactivity to MAGE-1 and Tyrosinase.
Presentation
PBS, pH 7.3, 0.09% Sodium Azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MLANA / Melan-A
Q16655 NM_005511 NP_005502.1

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 1/18/2022