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| Catalog Number | Size | Price |
|---|---|---|
| LS-C751137-100 | 100 µg (1 mg/ml) | $574 |
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Recombinant Monoclonal Rabbit anti‑Human MLANA / Melan‑A Antibody (clone MLANA/1761R, Azide‑free,Carrier‑free, IHC) LS‑C751137
Recombinant Monoclonal Rabbit anti‑Human MLANA / Melan‑A Antibody (clone MLANA/1761R, Azide‑free,Carrier‑free, IHC) LS‑C751137
Antibody:
MLANA / Melan-A Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (MLANA/1761R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free, Carrier-free
Other formats:
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
MLANA / Melan-A Rabbit anti-Human Recombinant Monoclonal (Azide-free, Carrier-free) (MLANA/1761R) Antibody
Application:
IHC-P
Reactivity:
Human
Format:
Unconjugated, Azide-free, Carrier-free
Other formats:
Specifications
Description
Melan-A antibody LS-C751137 is an unconjugated rabbit recombinant monoclonal antibody to human Melan-A (MLANA). Validated for IHC.
Target
Human MLANA / Melan-A
Synonyms
MLANA | Antigen LB39-AA | Antigen SK29-AA | Melan-A | Protein Melan-A | MART-1 | MART1 | Melan A
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Recombinant Monoclonal
Clone
MLANA/1761R
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Azide-free, Carrier-free.
Also available Unmodified.
Immunogen
Recombinant full-length hMART-1 protein. Antigen Molecular Weight: 20-22 kDa (doublet)
Specificity
This antibody recognizes a protein doublet of 20-22 kDa , identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Applications
- IHC - Paraffin (0.5 - 1 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistology (Formalin-fixed - 0.5-1 ug/ml for 30 minutes at RT - Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Presentation
10 mM PBS
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MLANA / Melan-A
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Species:
Human
Applications:
Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/1/2024
Date Requested: 5/1/2024
