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Antibodies > MBD1
MBD1 Antibody (aa98‑113) LS‑C743
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MBD1 antibody LS-C743 is an unconjugated rabbit polyclonal antibody to human MBD1. Validated for WB.
Catalog
Size
Price
LS-C743-100
100 µg (0.5 mg/ml)
$335
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Product Description

MBD1 antibody LS-C743 is an unconjugated rabbit polyclonal antibody to human MBD1. Validated for WB.
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Specifications

Target
Human MBD1
Synonyms
MBD1, CXXC3, RFT
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (2 µg/ml)
Immunogen
MBD1 antibody was raised against this antibody was developed by immunizing rabbits with a mixture of synthetic peptides corresponding to amino acids 98-113 (RQVGPQSGEVRKEAPR)and 391-405 (SESEDGAGSPPPYRR)of human MBD1, GenBank no ref|NP_056671.2|. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset (94%); Dog (88%); Bovine, Pig (81%).
Epitope
aa98-113
Specificity
A mixture of synthetic peptides corresponding to amino acids 98-113 and 342-356 of human MBD1.
Presentation
PBS, 0.02% Sodium Azide
Storage
Short term: 4°C; Long term: -70°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
About MBD1
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. Q9UIS9 NM_015846 NP_056671.2

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Images

Western blot

Western blot of MBD1 in HeLa cell lysate with anti-MBD1 pcAb. A protein band with an approximate molecular weight of 55 kD was detected.
Western blot of MBD1 in HeLa cell lysate with anti-MBD1 pcAb. A protein band with an approximate molecular weight of 55 kD was detected.

Western blot

Western blot of MBD1 in HeLa cell lysate with anti-MBD1 pcAb. A protein band with an approximate molecular weight of 55 kD was detected.
Western blot of MBD1 in HeLa cell lysate with anti-MBD1 pcAb. A protein band with an approximate molecular weight of 55 kD was detected.

Western blot

Western blot of MBD1 in HeLa cell lysate with anti-MBD1 pcAb. A protein band with an approximate molecular weight of 55 kD was detected.
Western blot of MBD1 in HeLa cell lysate with anti-MBD1 pcAb. A protein band with an approximate molecular weight of 55 kD was detected.

Western blot

Western blot of MBD1 in HeLa cell lysate with anti-MBD1 pcAb. A protein band with an approximate molecular weight of 55 kD was detected.
Western blot of MBD1 in HeLa cell lysate with anti-MBD1 pcAb. A protein band with an approximate molecular weight of 55 kD was detected.
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Requested From: United States
Date Requested: 10/15/2018
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