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MAD2B / REV7

MAD2 mitotic arrest deficient-like 2 (yeast)

Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.

Gene Name: MAD2 mitotic arrest deficient-like 2 (yeast)
Synonyms: MAD2L2, POLZ2, REV7 homolog, REV7, MAD2-like protein 2, MAD2B, HREV7
Target Sequences: NM_006341 NP_006332.3 Q9UI95

☰ Filters
Antibodies (21)
Proteins (5)
Over-Expression Lysate (4)
Primary (21)
Recombinant (1)
MAD2B / REV7 (26)
Human (20)
Mouse (7)
Rat (4)
IHC (6)
IHC-P (3)
WB (16)
ELISA (5)
IF (2)
IP (1)
Peptide-ELISA (1)
rabbit (19)
mouse (1)
rabbit-new zealand white (1)
Product Group
IHCPlus (1)
IgG (18)
polyclonal pc (21)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
N-Terminus (1)
aa198-231 (1)
No (26)
Myc-DDK (Flag) (5)
Human (3)
293T Cells (2)
HEK 293 Cells (3)
MAD2B / REV7 Antibody - Anti-MAD2L2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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MAD2B / REV7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$515
MAD2B / REV7 Antibody - Western blot analysis of extracts of various cell lines, using MAD2L2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.
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MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
MAD2B / REV7 Antibody - Immunohistochemical of paraffin-embedded H. kidney section using MAD2L2 Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
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MAD2B / REV7 Rabbit anti-Human Polyclonal (aa198-231) Antibody
Mouse
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
MAD2B / REV7 Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer tissue.
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MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
MAD2B / REV7 Antibody - 1:100 staining human breast carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MAD2B / REV7 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
Select
MAD2B / REV7 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$393
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
Select
MAD2B / REV7 Rabbit anti-Human Polyclonal Antibody
Human
Unconjugated
100 µg/$331
Select
MAD2B / REV7 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
MAD2B / REV7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
100 µg/$494
MAD2B / REV7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
100 µg/$494
MAD2B / REV7 Protein - Purified recombinant protein MAD2L2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
20 µg/$1,107
MAD2B / REV7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
24.2 kDa
20 µg/$150
Viewing 1-25 of 26 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).