MACF1

microtubule-actin crosslinking factor 1

Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Acts as a positive regulator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-regulated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of bulge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells.

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Antibodies (8)

Proteins (1)

Type

Primary (8)

Recombinant (1)

Target

MACF1 (9)

Reactivity

Human (8)

Mouse (2)

Rat (1)

Application

IHC (1)

WB (7)

ELISA (7)

IF (1)

Host

rabbit (2)

mouse (6)

Isotype

IgG (2)

IgG1,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (2)

Format

APC Conjugated (1)

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Unconjugated (3)

Epitope

aa1-95 (1)

aa1975-2025 (1)

Publications

No (9)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

Purification

Purified (1)

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MACF1 Antibody LS-C752716

Antibody:

MACF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

100 µg/$331

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MACF1 Antibody (aa1-95) LS-C309191

Antibody:

MACF1 Mouse anti-Human Monoclonal (aa1-95) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

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MACF1 Antibody (HRP) LS-C543026

Antibody:

MACF1 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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MACF1 Antibody (Biotin) LS-C522894

Antibody:

MACF1 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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MACF1 Antibody (FITC) LS-C532938

Antibody:

MACF1 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

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MACF1 Antibody (APC) LS-C514679

Antibody:

MACF1 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

Select

MACF1 Antibody (PE) LS-C651138

Antibody:

MACF1 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• APC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC
  • PE

Select

MACF1 Antibody (aa1975-2025) LS-C762083

Antibody:

MACF1 Rabbit anti-Human Polyclonal (aa1975-2025) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

Human MACF1 Protein (Recombinant GST, N-terminus) (aa1-95) - LS-G62015

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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