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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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M6PR Antibody (aa51‑100, Biotin) LS‑C445248
M6PR antibody LS-C445248 is a biotin-conjugated rabbit polyclonal antibody to M6PR from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C445248-100
100 µl (1 mg/ml)
$335

Popular M6PR Products

Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Mouse, Rat, Dog, Guinea pig, Pig, Rabbit
Applications: Western blot
Antibody
Species: Human, Monkey, Mouse, Rat, Bat, Horse, Pig
Applications: Peptide Enzyme-Linked Immunosorbent Assay
Antibody
Species: Mouse, Rat
Applications: IHC, Western blot
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
ICC/IF analysis of M6PR in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human M6PR antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
Species: Human
Applications: ICC, Western blot, Flow Cytometry, ELISA

Product Description

M6PR Antibody (aa51-100, Biotin) for WB/Western LS-C445248

Specifications

Target
Human M6PR
Synonyms
M6PR, CD-MPR, SMPR, MPR46, MPRD, Mr 46,000 Man6PR, CD Man-6-P receptor, MPR 46, MPR-46
Host
Rabbit
Reactivity
Human, Chimpanzee, Gibbon, Mouse, Rat, Dog, Guinea pig, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Orangutan, Monkey, Bat (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with HRP, FITC.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot
  • (applications tested for the base form of this product only)
Immunogen
M6PR antibody was raised against synthetic peptide located between aa51-100 of human M6PR (P20645, NP_002346). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Mouse, Rat, Rabbit, Pig, Guinea pig (100%); Orangutan, Marmoset, Elephant, Panda, Bat (92%); Dog, Horse (85%); Bovine (84%).
Epitope
aa51-100
Specificity
Human M6PR
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
About M6PR
Targeting of newly synthesized lysosomal enzymes in many cell types depends on formation of mannose 6-phosphate residues on lysosomal enzymes and recognition of these residues by specific receptors. The cation-dependent mannose 6-phosphate receptor is one of the two transmembrane proteins involved in transport of lysosomal enzymes. Binding of ligands to this receptor is dependent on divalent cations and pH. P20645 NM_002355 NP_002346.1


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Images

Western blot

Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 10/21/2018

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