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Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
Gene Name: | leukotriene B4 receptor 2 |
Family/Subfamily: | GPCR , Chemoattractant |
Synonyms: | LTB4R2, BLT2, BLTR2, Blt-2, BLT2R, JULF2, LTB4-R2, Hblt2, KPG_004, Leukotriene B4 receptor 2, Leukotriene B4 receptor BLT2, LTB4 receptor JULF2, LTB4-R 2 |
Target Sequences: | NM_019839 NP_062813.2 Q9NPC1 |
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