|
|
Legumain antibody LS-C474232 is a biotin-conjugated rabbit polyclonal antibody to Legumain (LGMN) from human, mouse, rat and other species. Validated for WB.
Print This Page
Technical Help
Review This ProductPopular LGMN / Legumain Products
Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Sheep
Applications:
Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Product Description
Legumain antibody LS-C474232 is a biotin-conjugated rabbit polyclonal antibody to Legumain (LGMN) from human, mouse, rat and other species. Validated for WB.
Specifications
Target
Human LGMN / Legumain
Synonyms
LGMN, AEP, LGMN1, Protease, cysteine 1, Asparaginyl endopeptidase, Cysteine protease 1, Legumain, PRSC1
Host
Rabbit
Reactivity
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Sheep
(tested or 100% immunogen sequence identity)
Predicted
Bat, Horse, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
- Western blot
- (applications tested for the base form of this product only)
Immunogen
LGMN / Legumain antibody was raised against synthetic peptide located between aa214-263 of human LGMN (Q99538, NP_005597). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Mouse, Rat, Sheep, Elephant, Panda, Dog, Bovine, Rabbit, Opossum (100%); Bat, Horse, Xenopus, Salmon, Pufferfish, Zebrafish (92%); Turkey, Zebra finch, Chicken, Lizard, Catfish, Stickleback, Medaka (85%).
Epitope
aa214-263
Specificity
Human LGMN / Legumain
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
About LGMN / Legumain
LGMN / Legumain is a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells.
Q99538
NM_005606
NP_005597.3
Publications (0)
Customer Reviews (0)
Images
Western blot
LGMN / Legumain antibody Western Blot of Fetal Brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
LGMN / Legumain antibody Western Blot of Fetal Brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
LGMN / Legumain antibody Western Blot of Fetal Brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
LGMN / Legumain antibody Western Blot of Fetal Brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Requested From: United States
Date Requested: 11/12/2018
Date Requested: 11/12/2018
