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Legumain antibody LS-C474232 is a biotin-conjugated rabbit polyclonal antibody to Legumain (LGMN) from human, mouse, rat and other species. Validated for WB.
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Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Sheep
Applications:
Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Product Description
Legumain antibody LS-C474232 is a biotin-conjugated rabbit polyclonal antibody to Legumain (LGMN) from human, mouse, rat and other species. Validated for WB.
About LGMN / Legumain
LGMN / Legumain is a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells.
Q99538
NM_005606
NP_005597.3
LGMN Antibody, AEP Antibody, LGMN1 Antibody, Protease, cysteine 1 Antibody, Asparaginyl endopeptidase Antibody, Cysteine protease 1 Antibody, Legumain Antibody, PRSC1 Antibody
Specifications
Target
Human LGMN / Legumain
Host
Rabbit
Reactivity
Human, Chimpanzee, Orangutan, Gibbon, Monkey, Mouse, Rat, Bovine, Dog, Rabbit, Sheep
(tested or 100% immunogen sequence identity)
Predicted
Bat, Horse, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
- Western blot
- (applications tested for the base form of this product only)
Immunogen
LGMN / Legumain antibody was raised against synthetic peptide located between aa214-263 of human LGMN (Q99538, NP_005597). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Mouse, Rat, Sheep, Elephant, Panda, Dog, Bovine, Rabbit, Opossum (100%); Bat, Horse, Xenopus, Salmon, Pufferfish, Zebrafish (92%); Turkey, Zebra finch, Chicken, Lizard, Catfish, Stickleback, Medaka (85%).
Epitope
aa214-263
Specificity
Human LGMN / Legumain
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS
Storage
Short term: store at 4°C. Long term: add glycerol to 40-50%, aliquot to avoid freeze-thaw cycles, and store at -20°C. Protect from light.
Restrictions
For research use only.
Publications (0)
Customer Reviews (0)
Images
Western blot
LGMN / Legumain antibody Western Blot of Fetal Brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
LGMN / Legumain antibody Western Blot of Fetal Brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
LGMN / Legumain antibody Western Blot of Fetal Brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
LGMN / Legumain antibody Western Blot of Fetal Brain. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Requested From: United States
Date Requested: 9/20/2018
Date Requested: 9/20/2018
