Recombinant Monoclonal Rabbit anti‑Human LGALS1 / Galectin 1 Antibody (clone GAL1/2499R, Azide‑free,Carrier‑free, aa12‑108, IHC) LS‑C751249
Recombinant Monoclonal Rabbit anti‑Human LGALS1 / Galectin 1 Antibody (clone GAL1/2499R, Azide‑free,Carrier‑free, aa12‑108, IHC) LS‑C751249
Antibody:
LGALS1 / Galectin 1 Rabbit anti-Human Recombinant Monoclonal (aa12-108) (Azide-free, Carrier-free) (GAL1/2499R) Antibody
Application:
IHC-P, ELISA
Format:
Unconjugated, Azide-free, Carrier-free
Overview
Antibody:
LGALS1 / Galectin 1 Rabbit anti-Human Recombinant Monoclonal (aa12-108) (Azide-free, Carrier-free) (GAL1/2499R) Antibody
Application:
IHC-P, ELISA
Format:
Unconjugated, Azide-free, Carrier-free
Specifications
Description
Galectin 1 antibody LS-C751249 is an unconjugated rabbit recombinant monoclonal antibody to human Galectin 1 (LGALS1) (aa12-108). Validated for ELISA and IHC.
Target
Human LGALS1 / Galectin 1
Synonyms
LGALS1 | 14 kDa lectin | 14 kDa laminin-binding protein | 14 kd lectin | GAL1 | Galectin 1 | Galectin-1 | HBL | Lactose-binding lectin 1 | Galaptin | GBP | HLBP14 | HPL | S-Lac lectin 1 | Gal-1
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Recombinant Monoclonal
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Azide-free, Carrier-free.
Also available
Unmodified.
Immunogen
Recombinant human Galectin-1 protein fragment (aa12-108). Antigen Molecular Weight: 14 kDa
Specificity
Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
Applications
- IHC - Paraffin (0.5 - 1 µg/ml)
- ELISA (2 - 4 µg/ml)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Usage
ELISA (Use Ab at 2-4 ug/ml for coating) - Immunohistology (Formalin-fixed - 0.5-1 ug/ml for 30 min at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.
Storage
Store at -20°C to -80°C for up to 2 years.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About LGALS1 / Galectin 1
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
Western blot, ELISA
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Mouse
Applications:
Western blot
Species:
Cow, Bovine
Applications:
Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/16/2024