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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LEPR / Leptin Receptor Antibody (aa829‑841) IHC‑plus™ LS‑B3013 Best Seller
Note: This antibody replaces LS-C34670, LS-C71627, LS-C71626
Leptin Receptor antibody LS-B3013 is an unconjugated goat polyclonal antibody to human Leptin Receptor (LEPR). Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B3013-50
50 µg (0.5 mg/ml)
$425

Popular LEPR / Leptin Receptor Products

Antibody
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Antibody
Species: Rat, Mouse
Applications: Western blot, ELISA
Anti-Leptin Receptor antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, ELISA
Antibody
Species: Rat
Applications: IHC, Immunofluorescence

Product Description

Leptin Receptor antibody LS-B3013 is an unconjugated goat polyclonal antibody to human Leptin Receptor (LEPR). Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.

Specifications

Target
Human LEPR / Leptin Receptor
Synonyms
LEPR, CD295 antigen, HuB219, LEP-R, OB receptor, LEPRD, OB-R, OBR, CD295, DB, Leptin receptor
Host
Goat
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Monkey, Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (4 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:16000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide C-TQDDIEKHQSDAG from an internal region of human LEPR / Leptin Receptor (NP_002294.2; NP_001003679.1; NP_001003680.1). Percent identity by BLAST analysis: Human, Gorilla (100%); Marmoset, Panda, Dog, Horse (92%).
Blocking Peptide
LS-E26104 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B3013. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa829-841
Specificity
Human LEPR / Leptin Receptor. This antibody is expected to recognise all three reported isoforms (NP_002294.2; NP_001003679.1; NP_001003680.1).
Usage
Immunohistochemistry: LS-B3013 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B3013 was determined to be 4 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About LEPR / Leptin Receptor
LEPR / Leptin Receptor belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. P48357 NM_002303 NP_002294.2


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Images

Immunohistochemistry

Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.

Immunohistochemistry

Anti-Leptin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Anti-Leptin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.

Western blot

Western blot of human brain lysate
Western blot of human brain lysate

Immunohistochemistry

Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.

Immunohistochemistry

Anti-Leptin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Anti-Leptin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.

Western blot

Western blot of human brain lysate
Western blot of human brain lysate

Immunohistochemistry

Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.

Immunohistochemistry

Anti-Leptin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Anti-Leptin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.

Western blot

Western blot of human brain lysate
Western blot of human brain lysate

Immunohistochemistry

Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Anti-Leptin Receptor antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.

Immunohistochemistry

Anti-Leptin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.
Anti-Leptin Receptor antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 4 ug/ml.

Western blot

Western blot of human brain lysate
Western blot of human brain lysate

Requested From: United States
Date Requested: 11/13/2018

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