Human KRT76 / Keratin 76

Rabbit

Human (tested or 100% immunogen sequence identity)

IgG Recombinant Monoclonal

KRTH/1576R

Unconjugated

Protein A/G purified

Unmodified. Also available Azide-free, Carrier-free.

Recombinant full-length human KRT76 protein. Antigen Molecular Weight: 52-67 kDa

This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1) - 64 kDa (CK3) - 59 kDa (CK4) - 58 kDa (CK5) - 56 kDa (CK6) - 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40 kDa . MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

• IHC - Paraffin (0.25 - 0.5 µg/ml)

Immunohistology (Formalin-fixed - 0.25-0.5 ug/ml for 30 min at RT - Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.) Optimal dilution for a specific application should be determined.

10 mM PBS, 0.05% BSA, 0.05% Sodium Azide

Store at 2°C to 8°C for up to 2 years.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q01546 NCBI: NM_015848 NP_056932.2