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Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.
Gene Name: | kinesin family member 16B |
Synonyms: | KIF16B, C20orf23, DJ971B4.1, KIAA1590, Kinesin motor protein, Kinesin-like protein KIF16B, SNX23, Sorting nexin 23, Sorting nexin-23, Kinesin family member 16B, KISC20ORF |
Target Sequences: | NM_024704 NP_078980.3 Q96L93 |
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