Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
KCNJ6 / GIRK2 antibody was raised against epitope: GST fusion protein with sequence ELANRAEVPLSWSVS SKLNQHAELETEEEEKNPEELTERNG, corresponding to residues 374-414 of mouse GIRK2 (Accession P48542) Epitope location: Intracellular, C-terminal part. Percent identity by BLAST analysis: Mouse (100%); Rat, Hamster (93%); Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Goat, Elephant, Panda, Dog, Bat, Opossum (87%); Platypus (80%).
Recognizes GIRK2. Species cross-reactivity.
Suitable for use in ELISA, Western Blot, Immunohistochemistry. Western Blot: 1:200. Rat brain membranes. Immunohistochemistry: Rat brain sections.
This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.