Target
Human KAT2B / PCAF
Synonyms
KAT2B | CREBBP-associated factor | GCN5 | Histone acetyltransferase PCAF | K(lysine) acetyltransferase 2B | Lysine acetyltransferase 2B | Histone acetylase PCAF | PCAF | p300/CBP-associated factor | CAF | GCN5L
Reactivity
Human
(tested or 100% immunogen sequence identity)
Immunogen
C-Terminus domain of human PCAF.
Specificity
Recognizes the C-terminal domain of PCAF protein. This region of PCAF has intrinsic acetyltransferase activity with core histones (H3 and H4), and with nucleosome core particles to promote transcriptional activation. It also acetylates p53 protein in response to DNA damage.