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ITGB4 / Integrin Beta 4

integrin, beta 4

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: integrin, beta 4
Family/Subfamily: Integrin , not assigned-Integrin
Synonyms: ITGB4, CD104, Integrin beta-4, Integrin Beta 4, gp150, CD104 antigen, Integrin beta-4 subunit, Integrin, beta 4
Target Sequences: NM_000213 NP_000204.3 P16144

Publications (3)

1
Role of Integrin ß4 in Lung Endothelial Cell Inflammatory Responses to Mechanical Stress. Chen W, Epshtein Y, Ni X, Dull RO, Cress AE, Garcia JG, Jacobson JR. Scientific reports. 2015 5:16529. (IP; Human) [Full Text Article] [PubMed:26572585] [PMC:PMC4647208] Related Antibodies: LS-C14098.
2
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article] [PubMed:31771627] [PMC:PMC6878650] Related Antibodies: LS-B3778.
3
A case of oral mucous membrane pemphigoid with IgG antibodies to integrin alpha 6 beta 4. Miyamoto S, Chikazu D, Yasuda T, Enomoto A, Oh-i T, Hirako Y, Tsuchisaka A, Yasukochi A, Sogame R, Teye K, Koga H, Ishii N, Qian H, Li X, Hashimoto T. The British journal of dermatology. 1995 Dec;171:1555-7. [Full Text Article] [PubMed:24836504] Related Antibodies: LS-B9845.

☰ Filters
Antibodies (92)
Proteins (10)
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ITGB4 / Integrin Beta 4 (105)
Human (81)
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rabbit (41)
mouse (43)
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monoclonal mc (50)
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ITGB4 / Integrin Beta 4 Antibody - Anti-Integrin Beta 4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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ITGB4 / Integrin Beta 4 Rat anti-Human Monoclonal (439-9B) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$460
ITGB4 / Integrin Beta 4 Antibody - Staining of the A549 cell line with 0.125 ug of Biotin Rat IgG2b Isotype Control (open histogram) or 0.125 ug of Biotin anti-human CD104 (439-9B) (colored histogram) followed by Sav-PE. Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ITGB4 / Integrin Beta 4 Rat anti-Human Monoclonal (Biotin) (439-9B) Antibody
Human
Flo
Biotin Conjugated
100 µg/$396
ITGB4 / Integrin Beta 4 Antibody - Anti-ITGB4 / Integrin Beta 4 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (aa1619-1822) (10B10D5) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
ITGB4 / Integrin Beta 4 Antibody - Staining of human tonsil cryostat section with Mouse anti-human CD104 (MOUSE ANTI HUMAN CD104).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (450-9D) Antibody
Human
Flo, IF, IHC, IHC-Fr, IP, WB
Unconjugated
25 µg/$281; 0.2 mg/$471
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (Azide-free) (450-9D) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Azide-free
500 µg/$668
ITGB4 / Integrin Beta 4 Antibody - SDS-PAGE Analysis of Purified, BSA-Free Integrin Beta-4 Antibody (clone UM-A9). Confirmation of Integrity and Purity of the Antibody.
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (UM-A9) Antibody
Human
Block, Flo, IF
Unconjugated
20 µg/$371; 100 µg/$574
ITGB4 / Integrin Beta 4 Antibody - IHC of rat vaginal epithelium using ITGB4 / Integrin Beta 4 Antibody.
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ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal (aa1809-1822) Antibody
Rat, Human
IHC, IHC-Fr, IP
Unconjugated
100 µl/$842
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (aa28-710) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$896
ITGB4 / Integrin Beta 4 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Integrin beta4 Antibody. The picture on the right is blocked with the synthesized peptide.
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ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal (aa1481-1530) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ITGB4 / Integrin Beta 4 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using ITGB4 Antibody at dilution of 1:100
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ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
ITGB4 / Integrin Beta 4 Antibody - 1:100 staining human lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal Antibody
Human
Flo, Func, IHC, IHC-Fr, IP
Unconjugated
100 µg/$854
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ITGB4 / Integrin Beta 4 Sheep anti-Human Polyclonal (Extracellular Domain) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µg/$919
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ITGB4 / Integrin Beta 4 Rat anti-Mouse Monoclonal (346-11A) Antibody
Mouse
IHC, IHC-Fr, IP, WB
Unconjugated
500 µg/$558
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
Flo, IHC, IP
Biotin Conjugated
100 µl/$1,054
ITGB4 / Integrin Beta 4 Antibody - CD104 Antibody in Immunohistochemistry (IHC)
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (Amino Acid: 1619-1822) (10B10D5) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
ITGB4 / Integrin Beta 4 Antibody - Immunohistochemical analysis of CD104 (pY1510) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal (pY1510) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal Antibody
Human
Flo, WB
Unconjugated
100 µg/$626
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (FITC) (UMA9) Antibody
Human
Flo, Func, WB
FITC Conjugated
120 Tests/$511
ITGB4 / Integrin Beta 4 Antibody - Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using CD104 mouse mAb with DAB staining.
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (1D6B4) Antibody
Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µl/$459
ITGB4 / Integrin Beta 4 Antibody - Immunohistochemical analysis of paraffin-embedded stomach cancer tissues using CD104 mouse mAb with DAB staining.
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (5G3G5) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µl/$459
ITGB4 / Integrin Beta 4 Antibody - Immunohistochemistry on frozen section of human skin showing strong staining of basal membrane (e.g. cells of sebaceous gland and sweat gland and cells forming the hair in the hair shaft) and connective tissue; no staining of muscle cells
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ITGB4 / Integrin Beta 4 Mouse anti-Human Monoclonal (58XB4) Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IP, WB
Unconjugated
0.1 mg/$424
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ITGB4 / Integrin Beta 4 Rat anti-Mouse Monoclonal (346-11A) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
0.5 mg/$403
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ITGB4 / Integrin Beta 4 Rat anti-Mouse Monoclonal (Azide-free, Low Endotoxin) (346-11A) Antibody
Mouse
Flo, IHC, IHC-Fr, IP, WB
Unconjugated, Azide-free, Low Endotoxin
0.5 mg/$448
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ITGB4 / Integrin Beta 4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$331
Viewing 1-25 of 105 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).