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| Catalog Number | Size | Price |
|---|---|---|
| LS-C204370-0.1 | 0.1 mg (1 mg/ml) | $316 |
Monoclonal Mouse anti‑Human ITGB2 / CD18 Antibody (clone MEM‑148, Low Endotoxin, WB) LS‑C204370
Monoclonal Mouse anti‑Human ITGB2 / CD18 Antibody (clone MEM‑148, Low Endotoxin, WB) LS‑C204370
Antibody:
ITGB2 / CD18 Mouse anti-Human Monoclonal (Low Endotoxin) (MEM-148) Antibody
Application:
WB, IP, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Low Endotoxin
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
ITGB2 / CD18 Mouse anti-Human Monoclonal (Low Endotoxin) (MEM-148) Antibody
Application:
WB, IP, Flo, Func
Reactivity:
Human
Format:
Unconjugated, Low Endotoxin
Specifications
Description
CD18 antibody LS-C204370 is an unconjugated mouse monoclonal antibody to human CD18 (ITGB2). Validated for Flow, Func, IP and WB.
Target
Human ITGB2 / CD18
Synonyms
ITGB2 | CD18 antigen | CD18 | Integrin beta chain, beta 2 | LCAMB | MAC-1 | MFI7 | MF17 | Integrin beta-2 | LAD | LFA-1
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Non-Reactivity
Porcine
Clonality
IgG1
Monoclonal
Clone
MEM-148
Conjugations
Unconjugated
Purification
Purified by protein-A affinity chromatography. Greater than 95% by SDS-PAGE.
Modifications
Low Endotoxin
Immunogen
Peripheral blood mononuclear cells
Specificity
The antibody MEM-148 recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit; beta2 integrin) is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.
Applications
- Western blot
- Immunoprecipitation
- Flow Cytometry (1 - 5 µg/ml)
- Functional Assay
Usage
The antibody MEM-148 induces homotypic cell aggregation and high-affinity LFA-1 conformation in resting leukocytes.
Presentation
Sterile PBS, pH 7.4, Azide free
Storage
Store at 2°C to 8°C. Do not freeze.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ITGB2 / CD18
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Species:
Human
Applications:
Western blot, Immunoprecipitation, Flow Cytometry
Species:
Human, Mouse, Rat
Applications:
Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
Flow Cytometry, Functional Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/29/2024
Date Requested: 4/29/2024
